Hamot Hospital was founded as the Hamot Hospital Association on February 7, 1881. The  hospital was named after Pierre Simon Vincent Hamot, a successful French  businessman who had settled in Erie in the early 19th century and  became an active member of the community. Following his death in 1846,  his children and grandchildren donated the Hamot Homestead for use as a  general hospital. Hamot’s heirs, on the ninth day of April, 1881,  conveyed to the association a large building on a lot of land that  measured 216 x 165 x 106 feet along State, Front and Second street. The  valuation of the property at that time was placed at $12,000. Quickly  organized and managed by the first nurse hired by the hospital, Irene  Sutleff, the hospital opened its doors to the public on July 1, 1881,  and Dr. David Hayes Strickland treated its first patient, who was  admitted on July 10, 1881. That same year, Hamot begun providing medical  treatment to the area’s sailors through the Marine Hospital Service, a  system in which the state reimbursed the hospital for their care, the  system continued throughout the 1910s. The Hamot Homestead facility  quickly outgrew its 25 patient capacity, and the first of many  expansions were begun in 1888.
To  ensure that everyone received the services of the hospital, without  barriers, in the spring of 1894, George Selden, bequeathed $20,000 to  the Hamot Hospital Association upon conditions that the hospital should  be made entirely non-sectarian, and the hospital was reorganized upon  that basis.
The  hospital’s namesake, Pierre Simon Vincent Hamot, was a son of Marie  Simon Hamot and Cecilia (Vandeperre) Hamot of Paris, France. Hamot came  to America, with his father, in 1802, as a private secretary to the  French consul at Philadelphia. The first years of his residence in the  United States were spent in eastern cities, including Philadelphia, New  York and Newport, Rhode Island. Upon his father’s death he set out for  Canada, where he made a small fortune in the mercantile business. The  salt trade and other mercantile activities brought him to Erie in 1805,  which he had first visited while en route to Detroit, Michigan.
One  of Erie’s most enterprising citizens, when Erie was a remote settlement  in the wilderness, Hamot made it an outpost of opportunity for himself.  As Hamot grew to become one of the area’s most successful merchants, he  became a partner with Rufus Reed in the Bank of Erie, the community’s  first banking institution. He was one of the founders and principal  stockholders in of Erie’s early newspapers, the Erie Weekly Observer. He  was a leader in the community, holding the offices of Canal  Commissioner of Pennsylvania and Superintendent of the United States  Public Works of Erie — On April 11, 1825, the Pennsylvania legislature  established the Board of Canal Commissioners to oversee the construction  and maintenance of the State of Pennsylvania’s canal system, which the  Erie Extension Canal ran, north to south, near the western edge of the  state, through Crawford and Erie counties.
Slavery  was an acceptable practice among the early settlers of Erie. Settlers  engaged in the practice were Rufus Reed, John Grubb, the Kelso family,  and Pierre Simon Vincent Hamot, to name a few. The first step toward  abolishing slavery in Pennsylvania came with the passage of the Gradual  Abolition Act of 1780. Slaves born before March 1 of that year remained  slaves for life; those born after March 1 would be freed at the age of  28. Slaves freed under gradual abolition became indentured servants  until their terms expired. Though the citizenry commonly referred to  these individuals as indentured servants, they were in fact considered  the property of those who held them.
Tax  records, from 1820, showed Hamot to be the third largest property owner  in the Borough of Erie. Among Hamot’s holdings included at least one  indentured servant — a nineteen-year-old black boy bound to serve until  the age of 28. When Hamot first came to Erie he lived in a two-story  brick home on German Street. His store was located on French Street, two  doors away from a black man named Robert Vosburgh who owned a barber  shop at his residence. Vosburgh played an important role on the  Underground Railroad. It is likely that Vosburgh had a hand in the  escape of Hamot’s Negro Boy Servant.
Seeking  the return of his property, Hamot, at the time, ran an advertisement  for the return of his property, a negro slave, as follows: "No mark but  the mark of Cain — six cents for the return of a negro servant, 19 years  of age. He is a very bad subject and is capable of every bad deed."
In  1827, Hamot’s German Street home was destroyed by fire and he hired  Peter Grawotz, the city’s first recorded brick mason, to construct a new  residence on the southwest corner of French and Third Streets. Hamot  died in 1846, leaving the house and property to his daughter Mary, who  later married George W. Starr, a founder of Hamot Hospital. The Starrs  moved to East Sixth Street, maintaining the French Street resident as  rental property. 
Hamot House, located at 302 French Street, has been restored and now houses the offices of the Hamot Second Century Foundation.
Timeline of Buildings and Grounds Projects at Hamot:
Hamot's First Major Addition (1888) 
Seldon-Scott Memorial Sections (1895) 
Hamot Hospital School of Nursing (1913) 
Private Pavilion (1914) 
Ward Wing - "Connecting Link" (1933) 
South Wing (1944) 
West Wing (1954) 
Main Wing (1960) 
North Complex (1960) 
Mental Health Center (1972) 
Professional Condominium (1974) 
South Complex (1977) 
Hamot House (renovated 1990-1991) 
Surgery Center (2001) 
Heart Institute (2003) 
Hamot Women's Hospital (2011)
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| Hamot Hospital (1900s) | 
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| Hamot Hospital (1920) | 
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| Hamot Hospital (1929) | 
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| Hamot Hospital (1933) | 
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| Hamot Hospital (1940s) |